Last reviewed: October 2026 · Cleared Peptides research team
Tesamorelin (TH9507) is a synthetic analog of the full 44-amino-acid growth-hormone-releasing hormone (GHRH) bearing an N-terminal trans-3-hexenoyl group. It is a reference agonist in GHRH-receptor research.
Tesamorelin Structure and Identifiers
| Name | Tesamorelin |
|---|---|
| Code | TH9507 |
| CAS number | 218949-48-5 |
| PubChem CID | 16137828 |
| Molecular formula | C221H366N72O67S |
| Molecular weight | ≈5135.9 g/mol |
| Length | 44 residues |
| Form | Lyophilized powder |
Design
Native GHRH is rapidly inactivated by dipeptidyl peptidase-4 cleavage at its N-terminus. The hexenoyl modification protects this site, a design studied in peptide-stability research.
Tesamorelin vs Ipamorelin
| Tesamorelin | Ipamorelin | |
|---|---|---|
| Receptor | GHRH receptor | GHS-R1a (ghrelin receptor) |
| Length | 44 residues | 5 residues |
See the ipamorelin guide.
This summary describes laboratory research only and makes no claim about effects in humans or animals.
Purity Testing and Storage
Every lot of Tesamorelin supplied by Cleared Peptides is tested by an independent laboratory for identity and purity (or composition, for multi-component preparations), and the lot Certificate of Analysis is published on our COA page. Store lyophilized Tesamorelin at −20 °C, sealed, dry and protected from light. Allow the vial to reach room temperature before opening and minimize freeze–thaw cycles. Handle according to your institution’s chemical-hygiene procedures.
Research materials referenced in this guide
Frequently Asked Questions
What receptor does tesamorelin act on?
The growth-hormone-releasing hormone receptor (GHRHR), a class B GPCR.
Is Tesamorelin for human use?
No. Cleared Peptides supplies Tesamorelin for laboratory research use only; it is not for human or veterinary use.
Selected References
Peer-reviewed literature on the compounds discussed in this guide, listed as scientific background for laboratory researchers. Citation does not imply endorsement by the authors or any use other than in-vitro research.
- Memdouh S, et al. Advances in the detection of growth hormone releasing hormone synthetic analogs. Drug Test Anal. 2021;13(11-12):1871-1887. PubMed 34665524 · DOI
Laboratory note: solubility depends on salt form and solvent. This guide does not state a single solubility figure. Handling of lyophilized material is described in the peptide storage guide.
Research Use Only Notice
This guide is provided for educational and laboratory reference purposes. It summarizes published, primarily in-vitro and structural research literature and does not describe, recommend or imply any use in humans or animals. Products sold by Cleared Peptides are for laboratory research use only; they are not drugs, foods, cosmetics or dietary supplements, are not FDA-approved, and are not intended to diagnose, treat, cure, mitigate or prevent any disease. No dosing, administration or therapeutic information is provided.
