Last reviewed: October 2026 · Cleared Peptides research team
This page lists the published identifiers for MOTS-c and for SS-31 when the two materials are supplied together. It does not describe a combined effect. Read each peptide on its own guide: MOTS-c and SS-31.
MOTS-c identifiers
| Name | MOTS-c |
|---|---|
| CAS number | 1627580-64-6 |
| PubChem CID | 146675088 |
| Molecular formula | C101H152N28O22S2 |
| Molecular weight | ≈2174.6 g/mol |
| Sequence | Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg |
| Length | 16 amino acids |
| Published biochemical note | MOTS-c is a peptide encoded in the mitochondrial 12S rRNA region. Literature discusses it in mitochondrial and metabolic signaling models. This page does not restate outcome claims from those studies. |
SS-31 identifiers
| Name | SS-31 (elamipretide) |
|---|---|
| Synonyms | MTP-131; Bendavia |
| CAS number | 736992-21-5 |
| PubChem CID | 11764719 |
| Molecular formula | C32H49N9O5 |
| Molecular weight | ≈639.8 g/mol |
| Sequence | D-Arg-Dmt-Lys-Phe-NH2 (Dmt = 2′,6′-dimethyltyrosine) |
| Published biochemical note | SS-31 is a tetrapeptide studied in laboratory work on cardiolipin binding in mitochondrial membranes. This page does not restate outcome claims from those studies. |
Research material
Selected References
Peer-reviewed literature listed as scientific background for laboratory researchers. Citation does not imply endorsement by the authors, and it is not a statement of benefit or use.
- Lee C, et al. The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance. Cell Metab. 2015;21(3):443-454. Cited here for the reported sequence and mitochondrial origin of MOTS-c. Outcome wording in the paper title is not repeated as a claim on this site. PubMed 25738459
- Szeto HH. First-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergetics. Br J Pharmacol. 2014;171(8):2029-2050. Cited for the SS-31 sequence and cardiolipin-binding description. Outcome wording in the paper title is not repeated as a claim on this site. PubMed 24117165
Laboratory note: solubility depends on salt form and solvent. This guide does not state a single solubility figure. Handling of lyophilized material is described in the peptide storage guide.
Research Use Only Notice
This guide is provided for educational and laboratory reference purposes. It summarizes published structural and biochemical literature. It does not describe, recommend, or imply any use in humans or animals. Products sold by Cleared Peptides are for laboratory research use only. They are not drugs, foods, cosmetics, or dietary supplements, are not FDA-approved, and are not intended to diagnose, treat, cure, mitigate, or prevent any disease. No dosing, administration, or use instructions are provided.
