Last reviewed: October 2026 · Cleared Peptides research team
HHB is an aqueous research blend of B-vitamin cofactors and related compounds. This page names each component and the enzyme pathway it is associated with in published biochemistry.
Component names match the product record. A CAS number is included only when the named chemical form has a public registry entry. Pathway notes describe published biochemistry. They are not statements of benefit or use.
Components
| Component | CAS number | Published biochemical note |
|---|---|---|
| Niacinamide | 98-92-0 | An amide of niacin and a precursor of the NAD and NADH cofactors in published redox pathways. |
| Thiamine HCl (B1) | 67-03-8 | The hydrochloride salt of thiamine. Enzyme pathways convert it to thiamine pyrophosphate, a cofactor of pyruvate dehydrogenase. |
| Pantothenic acid (B5) | 79-83-4 | The precursor that is built into coenzyme A. |
| Choline | Salt form is lot-specific. CAS is not stated here. | A precursor of phosphatidylcholine in published phospholipid pathways. |
| Inositol | 87-89-8 (myo-inositol) | A cyclitol in phosphatidylinositol membrane-lipid pathways. |
| Niacin (B3) | 59-67-6 | A precursor of the NAD and NADH cofactors. |
| Biotin (B7) | 58-85-5 | A cofactor of carboxylase enzymes in published fatty-acid and amino-acid pathways. |
| Folic acid (B9) | 59-30-3 | Converted to tetrahydrofolate cofactors that carry one-carbon units in published nucleotide pathways. |
| Riboflavin (B2) | 83-88-5 | A precursor of the FMN and FAD flavin cofactors. |
Solubility of the finished aqueous blend is a property of that formulation and is not given a single public figure here. See the lot COA.
HHB blend · NAD+ guide · COA page
Other names
HHB is the Cleared Peptides catalog name for this aqueous B-vitamin blend. It is not one molecule. Niacinamide, niacin, riboflavin, thiamine, pantothenic acid, biotin, folic acid, choline, and inositol each keep their own registry identity.
Published cofactor pathways
The notes below describe published enzyme pathways for the named chemicals. They are not studies of this blend as one substance, and they are not statements of benefit or use.
Niacinamide (CAS 98-92-0) and niacin (CAS 59-67-6) are precursors of the NAD and NADH cofactors. Riboflavin (CAS 83-88-5) is the precursor of FMN and FAD. Published nitric oxide synthase preparations require NADPH, FAD, and FMN along with the amino-acid substrate L-arginine. That cofactor list is why the niacin and riboflavin rows sit next to redox chemistry, not because this blend has been studied as one test article.
Thiamine HCl (CAS 67-03-8) is the salt that enzyme pathways convert toward thiamine pyrophosphate, the cofactor of pyruvate dehydrogenase. Pantothenic acid (CAS 79-83-4) is the precursor built into coenzyme A. Biotin (CAS 58-85-5) is the cofactor of carboxylase enzymes in published fatty-acid and amino-acid pathways. Folic acid (CAS 59-30-3) is converted to tetrahydrofolate cofactors that carry one-carbon units in published nucleotide pathways.
Myo-inositol (CAS 87-89-8) is the cyclitol in phosphatidylinositol lipids. Choline’s salt form is lot-specific, so this page does not assign it a CAS number; published pathways describe choline as a precursor of phosphatidylcholine. The NAD cofactor itself is covered on the NAD+ guide.
Frequently Asked Questions
Is HHB a single vitamin?
No. HHB is a blend. Each B-vitamin cofactor in the table is a separate chemical with its own CAS number, except choline, whose salt is named on the lot COA.
Why is choline missing a CAS number?
Choline is supplied as a salt, and different salts have different registry numbers. The lot COA is the salt record.
Is the HHB blend for human use?
No. It is supplied for laboratory research use only and is not for human or veterinary use.
Selected References
Peer-reviewed literature listed as scientific background for laboratory researchers. Citation does not imply endorsement by the authors, and it is not a statement of benefit or use. These papers do not study the finished blend as a single substance.
- Förstermann U, Sessa WC. Nitric oxide synthases: regulation and function. Eur Heart J. 2012;33(7):829-837. Cited here only for the enzyme fact that nitric oxide synthase uses L-arginine as a substrate and requires NADPH, FAD and FMN as cofactors. PubMed 21890489 · DOI
Research Use Only Notice
This guide is provided for educational and laboratory reference purposes. It summarizes published structural and biochemical literature. It does not describe, recommend, or imply any use in humans or animals. Products sold by Cleared Peptides are for laboratory research use only. They are not drugs, foods, cosmetics, or dietary supplements, are not FDA-approved, and are not intended to diagnose, treat, cure, mitigate, or prevent any disease. No dosing, administration, or use instructions are provided.
