Last reviewed: October 2026 · Cleared Peptides research team
BPC-157 (Body Protection Compound-157, also designated PL 14736) is a synthetic 15-amino-acid peptide whose sequence is derived from a protein found in gastric juice. It is one of the most widely studied short research peptides, used extensively in cell-culture and biochemical models.
In this guide:
BPC-157 Sequence and Identifiers
| Name | BPC-157 |
|---|---|
| Synonyms | Body Protection Compound-157; PL 14736; bepecin |
| CAS number | 137525-51-0 |
| PubChem CID | 9941957 |
| Molecular formula | C62H98N16O22 |
| Molecular weight | ≈1419.5 g/mol |
| Sequence | Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val |
| Physical form | Lyophilized white powder |
Stability
BPC-157 is noted in the literature for unusual stability in aqueous solution and in gastric-juice-like conditions compared with many short peptides — a property attributed to its proline-rich N-terminal region. This stability makes it practical as a reference peptide in longer-duration in-vitro experiments.
Published In-Vitro Research Areas
- Endothelial and fibroblast cell-migration (scratch/wound-closure) assays
- Nitric-oxide (NO) pathway signaling
- Growth-factor receptor signaling, including VEGFR2 and FAK–paxillin pathway studies
- Gene-expression studies (e.g. growth-hormone receptor expression in fibroblasts)
These are laboratory research models; this guide makes no claims about effects in humans or animals.
Research Formats Available
BPC-157 is often studied alongside TB-500 (Thymosin Beta-4). Cleared Peptides offers BPC-157, a BPC-157 + TB-500 blend, and the multi-component GLOW and KLOW blends. Each lot’s COA is on our COA page. Compare the two peptides in our BPC-157 vs TB-500 guide.
Research materials referenced in this guide
Frequently Asked Questions
What is BPC-157?
BPC-157 is a synthetic 15-residue peptide (pentadecapeptide) derived from a gastric protein sequence, used as a research peptide in cell-based models.
What is the CAS number of BPC-157?
137525-51-0; formula C62H98N16O22, MW ≈1419.5 g/mol.
How should BPC-157 be stored?
Lyophilized BPC-157 is stored at −20 °C, sealed, dry and protected from light.
Is BPC-157 for human use?
No. Cleared Peptides supplies BPC-157 for laboratory research use only.
Selected References
Peer-reviewed literature on the compounds discussed in this guide, listed as scientific background for laboratory researchers. Citation does not imply endorsement by the authors or any use other than in-vitro research.
- Sikiric P, et al. Stable gastric pentadecapeptide BPC 157-NO-system relation. Curr Pharm Des. 2014;20(7):1126-35. PubMed 23755725 · DOI
- Sikiric P, et al. Brain-gut Axis and Pentadecapeptide BPC 157: Theoretical and Practical Implications. Curr Neuropharmacol. 2016;14(8):857-865. PubMed 27138887 · DOI
Laboratory note: solubility depends on salt form and solvent. This guide does not state a single solubility figure. Handling of lyophilized material is described in the peptide storage guide.
Research Use Only Notice
This guide is provided for educational and laboratory reference purposes. It summarizes published, primarily in-vitro and structural research literature and does not describe, recommend or imply any use in humans or animals. Products sold by Cleared Peptides are for laboratory research use only; they are not drugs, foods, cosmetics or dietary supplements, are not FDA-approved, and are not intended to diagnose, treat, cure, mitigate or prevent any disease. No dosing, administration or therapeutic information is provided.
