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Last reviewed: October 2026 · Cleared Peptides research team

Mazdutide (LY3305677, IBI362) is a synthetic peptide described in public substance records as a GLP-1 receptor and glucagon receptor agonist. CAS 2259884-03-0. Formula C207H317N45O65 is the formula on the public compound record. It is not the same molecule as retatrutide, which is also studied at the GIP receptor.

Name Mazdutide
Other names LY3305677; LY-3305677; IBI362
CAS number 2259884-03-0
Molecular formula C207H317N45O65
Class GLP-1 receptor and glucagon receptor peptide
Catalog status Not a current Cleared Peptides lot.

Receptor class

Retatrutide is described at three receptors: GIP, GLP-1, and glucagon. Mazdutide’s public record is the two-receptor pair GLP-1 and glucagon. Survodutide and cotadutide are separate peptides in that same two-receptor group.

Frequently Asked Questions

What is the catalog or development code?

LY3305677 and IBI362.

Is mazdutide retatrutide?

No. Different CAS numbers. Retatrutide is CAS 2381089-83-2.

Is this for human use?

No. Laboratory reference only. No dosing is provided.

Selected References

Registry records and peer-reviewed literature listed as scientific background. Citation does not imply endorsement, a benefit, or any use.

  1. PubChem compound record for mazdutide, CID 167312357, CAS 2259884-03-0. PubChem 167312357

Research Use Only Notice

This guide is provided for educational and laboratory reference purposes. It summarizes published structural and biochemical literature. It does not describe, recommend, or imply any use in humans or animals. These materials are not drugs, foods, cosmetics, or dietary supplements on this page, are not offered here as a treatment, and no dosing or administration instructions are provided. Cleared Peptides does not currently list a lot for every compound on this page.

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