Last reviewed: October 2026 · Cleared Peptides research team
Selank (TP-7) is a synthetic heptapeptide developed at the Institute of Molecular Genetics, Moscow. It extends the immunomodulatory tetrapeptide tuftsin (Thr-Lys-Pro-Arg) with Pro-Gly-Pro for enzymatic stability.
Selank Structure and Identifiers
| Name | Selank |
|---|---|
| Synonyms | TP-7 |
| CAS number | 129954-34-3 |
| PubChem CID | 11765600 |
| Molecular formula | C33H57N11O9 |
| Molecular weight | ≈751.9 g/mol |
| Sequence | Thr-Lys-Pro-Arg-Pro-Gly-Pro |
| Form | Lyophilized powder |
Tuftsin Origin
Tuftsin is a tetrapeptide fragment of the IgG heavy chain. Selank keeps tuftsin’s sequence and adds the protease-resistant Pro-Gly-Pro motif also used in Semax.
Published Research Areas
- GABAergic-system gene-expression studies
- Cytokine-expression assays
- Enkephalinase-inhibition studies
This summary describes laboratory research only and makes no claim about effects in humans or animals.
Purity Testing and Storage
Every lot of Selank supplied by Cleared Peptides is tested by an independent laboratory for identity and purity (or composition, for multi-component preparations), and the lot Certificate of Analysis is published on our COA page. Store lyophilized Selank at −20 °C, sealed, dry and protected from light. Allow the vial to reach room temperature before opening and minimize freeze–thaw cycles. Handle according to your institution’s chemical-hygiene procedures.
Frequently Asked Questions
What is tuftsin?
A tetrapeptide (Thr-Lys-Pro-Arg) derived from the Fc region of immunoglobulin G, from which Selank was designed.
Is Selank for human use?
No. Cleared Peptides supplies Selank for laboratory research use only; it is not for human or veterinary use.
Selected References
Peer-reviewed literature on the compounds discussed in this guide, listed as scientific background for laboratory researchers. Citation does not imply endorsement by the authors or any use other than in-vitro research.
- Filatova E, et al. GABA, Selank, and Olanzapine Affect the Expression of Genes Involved in GABAergic Neurotransmission in IMR-32 Cells. Front Pharmacol. 2017;8:89. PubMed 28293190 · DOI
- Kozlovskii II, et al. The optimizing action of the synthetic peptide Selank on a conditioned active avoidance reflex in rats. Neurosci Behav Physiol. 2003;33(7):639-43. PubMed 14552529 · DOI
Laboratory note: solubility depends on salt form and solvent. This guide does not state a single solubility figure. Handling of lyophilized material is described in the peptide storage guide.
Research Use Only Notice
This guide is provided for educational and laboratory reference purposes. It summarizes published, primarily in-vitro and structural research literature and does not describe, recommend or imply any use in humans or animals. Products sold by Cleared Peptides are for laboratory research use only; they are not drugs, foods, cosmetics or dietary supplements, are not FDA-approved, and are not intended to diagnose, treat, cure, mitigate or prevent any disease. No dosing, administration or therapeutic information is provided.
